U.S. Vice President JD Vance is expected to travel to Islamabad, Pakistan, on April 21, a day after the second round of U.S.-Iran talks were expected to take place, as the United States likely waited for some indication that Iran would participate in upcoming talks, AP reported on April 21. Iranian officials told regional mediators that Tehran would send a delegation — which is set to arrive early April 22 — after Iranian Supreme Leader Mojtaba Khamenei reportedly approved participation late on April 20.