The U.S.-Egypt accord, one of the cornerstone bilateral relationships shaping stability in the Middle East and North Africa, will come under pressure as the Biden administration enters the White House promising greater scrutiny of Egyptian actions and as Egypt prioritizes regional stability in areas of less U.S. interest. Congress and the incoming Biden administration have already threatened the government of Egyptian President Abdel Fattah al-Sisi with sanctions and conditions on economic aid tied to human rights concerns. On top of this, Cairo is already reconsidering whether it needs to maintain its historic economic, security and diplomatic reliance on Washington at the same level. Even so, the United States is unlikely to terminate its substantial arms sales and aid to Egypt. Domestically, Egypt's focus on political and economic stability at the cost of personal freedoms will clash with the Biden administration's renewed focus on human rights.